Office of Research Infrastructure Programs (ORIP)

Examples of interest areas that ORIP may consider include:

• Support of alterations and renovations (A&R) of research facilities
• Purchase of instrument(s)/equipment critical for biomedical research
• Importation costs of a special collection to an ORIP supported repository

Principal Investigators are encouraged to speak to their eRA assigned Program Official before applying to discuss eligibility, need for the supplement, availability of funds, and application procedures.

General Inquiries:

Division of Comparative Medicine

[email protected]

• ORIP’s high-priority thematic areas for conferences and meetings are: 
  • Developing model resources to advance the study of human diseases 
  • Innovating cross-disciplinary research training in model systems 
• ORIP will only support research meetings that are held at domestic sites.
• For models-oriented conferences and meetings, proposals must be applicable to the research interests of two or more categorical NIH Institutes/Centers (ICs). 
  • Applications focused on a specific disease or category of research will not be accepted and should be proposed to the appropriate categorical IC of the NIH. 
  • Applications proposing conferences or scientific meetings that are predominantly of interest to one NIH IC and only peripherally of interest to other NIH ICs are not acceptable.
• For training-oriented conferences and meetings, applications with a primary focus on cross-disciplinary research training in model systems for early-career scientists will receive priority for consideration.

• Grants awarded by ORIP generally support only a portion of the entire cost of a conference or meeting. 
• ORIP typically provides nominal support between $5K and $10K for conferences or meetings.
• ORIP will consider support up to $75K only in highly compelling cases.
• Other ICOs may co-fund awards by ORIP for conferences or meetings above the support provided by ORIP.

• Applications can be submitted for any of the NIH standard due dates for R13 applications.

• ORIP typically accepts applications for up to 2 years of support across all areas of ORIP’s mission.
• ORIP will consider applications for up to 5 years of support only in highly compelling cases.

Office of Research Infrastructure Programs (ORIP)
Email: [email protected]

• ORIP supports research-oriented veterinarian scientists (D.V.M., V.M.D., or equivalent degree from an institution accredited by the American Veterinary Medical Association) proposing to develop independent research skills and gain experience in the methods, state-of-the art technologies, and experimental approaches required to advance modern biomedical research. 
• ORIP prioritizes applications that
  • Develop model systems, biomaterials, and technologies to address emerging human health needs, prevent disease, promote health, and advance foundational science
  • Advance the career development of veterinarian scientists to align with the management and use of comparative medicine resources
• ORIP encourages interdisciplinary collaborations and cross-training in essential and emerging areas, such as computational biology/bioinformatics, biostatistics, artificial intelligence/machine learning, science communication, science policy, and other relevant fields.
• ORIP supports career development applications that propose to develop leaders in human based models, including biology-centered in vivo modeling, artificial intelligence/machine learning, bioinformatics, tissue engineering, organoids, and organ-on-chip technology.

• A maximum of four years of protected time to develop awardee’s research career; however, the awardee is actively encouraged to apply for additional research grants anytime during the tenure of their K award.

ORIP will provide up to $75,000 plus fringe benefits per year for salary support.

ORIP will provide up to $20,000 direct costs per year for research support.

• Candidates are expected to commit a minimum of nine person months of effort (75% of full-time professional effort) to their program of career development during the mentored phase.
• In the final two years of the award, effort can be reduced, but not below 50%, provided recipient remains in a mentored status, and has successfully competed for research awards from NIH or any other Federal agency. 

Office of Research Infrastructure Programs (ORIP)
Email: [email protected]

• ORIP will consider applications for postdoctoral training of veterinarian scientists that provide innovative cross-disciplinary research training in model systems for human health and diseases. These applications can include advanced training in human-based models such as biology-centered in vivo modeling, artificial intelligence/machine learning, bioinformatics, tissue engineering, organoids, and organ-on-chip technology.
• The research accomplished under this training program should provide the trainees with the necessary tools to successfully compete for career development awards or independent grant funding. 
• This training may be incorporated into a research degree program.
• ORIP will not fund pre-doctoral or short-term (<18 months) training positions.

ORIP only supports trainees who hold a D.V.M., V.M.D., or equivalent degree from an institution accredited by the American Veterinary Medical Association.

• ORIP supports new and competing renewal applications up to 5 years of support and 6 trainee slots in any budget year.
• ORIP will provide up to 3 years of support for individual trainees.

Up to $1500 per year per trainee.

Office of Research Infrastructure Programs (ORIP)
Email: [email protected]

ORIP supports research projects to develop technology including, but not limited to, the following: 

• Create, characterize, or improve models of human disease; and develop new approach methodologies (NAMs) to complement or reduce the use of animal models in research. 
• Preservation, revival and monitoring of cells, tissue, organs or gametes from model systems. 
• Validate research models to enhance the rigor and reproducibility of pre-clinical studies. 
• Devices and technologies required for development and maintenance of conventional and NAM biological model systems, including those for advancing the care, welfare, housing, and management of these models; or sensor and monitoring technologies for the surveillance of models or environmental factors that lead to improved rigor and reproducibility for studies using these models.

General Inquiries:

ORIP Small Business

[email protected]