National Cancer Institute (NCI)

Mission Statement

The NCI Mission is to lead, conduct, and support cancer research across the nation to advance scientific knowledge and help all people live longer, healthier lives.


Interest Areas

General Topics

Cancer Biology: Supports research that advances fundamental understanding of the causes and biology of cancer, including cancer genomics, to improve prevention, detection, diagnosis, and treatment.

Cancer Prevention: Supports cancer prevention research to identify factors that cause cancer in humans and to develop risk-reduction strategies and preventive interventions.

Cancer Screening and Early Detection Research: Supports a variety of programs designed to improve early detection and enhance cancer screening.

Cancer Treatment, Diagnosis and Prognosis: Supports research to advance cancer treatment and disease control, as well as improve diagnosis, prognosis, screening, and early detection.

Cancer Control, Population Sciences, Survivorship, and Outcomes Research: Supports research to reduce cancer burden and improve quality of life for cancer survivors through effective methodology, interventions, and dissemination on a population-wide scale.

Cancer Training: Provides support to nonprofit and for-profit institutions and to individuals for biomedical training opportunities supporting careers in cancer research. 

Assistance Listing

Assistance listings are detailed public descriptions of federal programs used across government agencies that provide grants, loans, scholarships, insurance, and other types of assistance awards. They are maintained in the System for Award Management (SAM) and can be used to search for opportunities in Grants.gov.

View NCI Assistance Listing Numbers

  • 93.393 - Cancer Cause and Prevention Research
  • 93.394 - Cancer Detection and Diagnosis Research
  • 93.395 - Cancer Treatment Research
  • 93.396 - Cancer Biology Research
  • 93.397 - Cancer Centers Support Grants
  • 93.398 - Cancer Research Manpower
  • 93.399 - Cancer Control

Highlighted Topics

Title Lead ICO Participating ICOs Posted Date Expiration Date

Funding Opportunities and Notices

Search for NCI’s funding opportunities and notices


ICO Funding Policies and Considerations

Visit NIH Fiscal Policies for NIH-wide information on appropriations and other budgetary information (salary limits, stipends, tuition/fees) and Funding Decisions to learn about NIH's consistent and unified approach for making funding decisions.

NCI Funding Policies and Considerations builds on that general information.


Additional Information by Funding Category

Administrative Supplements
In addition to our Administrative Supplements overview, consider the following NCI-specific information.
Administrative Supplement Interest Areas:

NCI prioritizes funding new, renewal and ongoing grants and cooperative agreements  

  • The institute has limited flexibility to support administrative supplements.
  • Given this prioritization, the number of successful administrative supplement applications will likely be low in any given year.
  • Examples of unsolicited administrative supplement requests that NCI will generally consider are replacement of critical lab equipment and resources.
Administrative Supplement Due Dates:

NCI will accept and consider administrative supplement requests at any time through July 31. Requests received after July 31 will not be considered for funding.

Administrative Supplement Contact:

Program Contacts:

  • The NCI Program Official for the parent award 

Grants Management Contact

Conferences and Meetings
In addition to our Conferences and Meetings overview, consider the following NCI-specific information.
Conferences and Meetings Interest Areas:

Conferences and meetings may address any area of cancer research, including cancer biology, prevention, diagnosis, treatment, and cancer control. Appropriate topics include basic, translational, clinical, population-based, interdisciplinary, and emerging research that advances understanding of cancer etiology, progression, detection, survivorship, treatment and outcomes. Meetings may focus on presenting, developing, disseminating, or critically evaluating scientific knowledge; integrating emerging technologies, methods, or clinically relevant models; or advancing collaborative, multidisciplinary research. Topics may also address health drivers, implementation science, data and AI-driven research, workforce development, and HIV-associated cancers when directly relevant to cancer research. Applications not aligned with cancer research objectives are not responsive. Applicants are encouraged to contact NCI ([email protected]) at least six weeks prior to submission for guidance.

Conferences and Meetings Budget Considerations:

NCI has limited discretionary funds to support conferences and meetings that advance its mission to drive progress in cancer research. Budgets must be well justified and aligned with the meeting’s scope, scale, and expected impact. Awards depend on fiscal constraints and program priorities. Applicants should contact NCI ([email protected]) at least six weeks before submission for guidance.

Conferences and Meetings Key Date Considerations:

 Consistent with the associated R13/U13 NOFO and NIH policy, NCI will not issue a conference grant award unless the Federal award date precedes the conference start date.

Conferences and Meetings Project Period Considerations:

NCI typically considers applications requesting one year of support. Applicants seeking up to five years in a single application should consult with NCI ([email protected] ) at least six weeks before submission. The associated R13/U13 NOFO requires additional details for each proposed future year to inform peer review.

Conferences and Meetings Contacts:

Scientific Program Contact:  
NCI Referral Officer
Email: [email protected] 

Grants Management Contact:
Office of Grants Administration
[email protected] 

Individual Fellowship
In addition to our Individual Fellowships Overview, consider the following NCI-specific information.
Individual Fellowships Interest Areas:
  • The National Cancer Institute (NCI) supports fellowships in all areas of cancer research, including cancer prevention, control, behavioral sciences, population sciences, and translational research. 
  • NCI supports funding for topics with a clear cancer focus in the research training plan.  
Individual Fellowships Key Date Considerations:

F99/K00: K00 applications must be submitted directly to the assigned F99 Program Director six (6) months prior to the proposed activation date of the K00 award. This will also ensure the transition to the K00 postdoctoral phase takes place without interruption in funding. K00 applications may only be submitted by PIs with an F99 award. 

Individual Fellowships Project Period Considerations:
NCI may limit project periods for specific education activities, as follows:

F99/K00: K00 project period is three (3) years with the possibility to request adding a fourth year with strong justification for an additional year of training. These requests will be evaluated by program on a case-by-case basis.  

Individual Fellowships Budget Considerations:
In addition to current NRSA stipends, tuition/fees, and other budgetary levels, NCI may apply the following limits to applicable awards:

F99 

  • Travel to mandatory NCI annual meeting during F99 (year 1) and following transition to K00 award (year 1): $1,500 

K00 

  • Salary: up to $80,000/year with budget justification. Salary support must be commensurate with the base salary that would have been paid by the institution with which the individual is affiliated with when the award is issued.  
  • Research and career development: $30,000/year  

NCI gives funding priority to applications that: 

  • Indicate funds are available to support the candidate’s research training plan throughout the duration of the award. 
  • The proposed scientific research question or approach is distinct from the mentor’s pending or active grants, and there is no substantial text duplication of the mentor’s specific aims. 
Individual Fellowships Contacts:
Research Education
In addition to our Research Education overview, consider the following NCI-specific information.
Research Education Interest Areas:
  • The National Cancer Institute (NCI) supports research education in all areas of cancer research, including cancer prevention, control, behavioral sciences, population sciences, and translational research. 
  • The NCI provides support for educational activities that complement and/or enhance the training of a cancer research workforce to meet the nation’s biomedical, behavioral and clinical research needs. Applications should propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients. 
  • In the notice of funding opportunity for the Courses for Skills Development and Curriculum or Methods Development, NCI will prioritize funding of applications that are focused on Courses for Skills Development. 
  • The NCI Youth Enjoy Science program supports multi-component applications with educational activities such as research experiences, curriculum or methods development, and outreach. These programs should inspire middle school, high school, and undergraduate students to pursue biomedical cancer research, outline career paths across the cancer continuum, and strengthen research skills. Research experiences can also include middle and high school teachers and undergraduate faculty. 
Research Education Participants:
NCI prioritizes funding for participants in the following areas:
  • Undergraduate
  • Predoctoral
  • Postdoctoral/Residency
  • Early Career
  • Other

    Healthcare providers and allied health professionals; Middle school and high school students and teachers (NCI Youth Enjoy Science program) 

Research Education Budget Considerations:
NCI may limit budgets for specific education activities, as follows:
  • Courses for Skills Development: $300,000 
  • Curriculum or Methods Development: $150,000 
  • Research Experiences: $300,000 
  • Mentoring Activities & Networks: $300,000 
  • Youth Enjoy Science program: $400,000 
Research Education Personnel, Participant, and Other Program-Related Costs:
NCI may limit awarded budgets for personnel, participant, and other costs, as follows:

Courses for Skills Development and Mentoring Activities & Networks 

  • Personnel costs: 

  • Up to $150,000 Direct Costs/Year, Including Consultants 

  • Up to 3 Calendar Months for Total PI(s) Effort 

  • Participant costs: 

  • Course-Related Expenses: Up to $500 

  • Housing and Per Diem: Up to $300 per day of the course 

  • Round-Trip Travel to/from R25 Course Site, as needed 

  • Other program-related expenses: Travel, Equipment, Supplies, Consultants (subject to personnel budget cap), etc. 

Curriculum or Methods Development 

  • Personnel costs:  As Appropriate 

  • Participant costs: Not Applicable 

  • Other program-related expenses: Travel, Equipment, Supplies, Consultants, etc. 

Research Experiences 

  • Personnel costs: Based on Number of Participants (N): Up to ($4,500 x N) Direct Costs/Year, Including Consultants 

  • Participant costs: 

  • Subsistence: Up to $15/Hour or $9,000 for 15 Weeks 

  • Full-time Research Education-Related Expenses: Up to $1,000 

  • Housing Allowance: Up to $1,000 

  • Round-Trip Travel to/from R25 Course Site, as needed 

  • Other program-related expenses: Travel, Equipment, Supplies, Consultants, (subject to personnel budget cap), etc. 

Youth Enjoy Science program 

  • Personnel Costs: Up to $4,500 (Direct Costs) is allowed for personnel (including consultants) 

  • Participant Costs: Allowable participant costs depend on the educational level/career status of the individuals to be selected to participate in the program. 

  • Other program-related expenses:  

  • Up to $1,500 per participant per year is allowed for research education-related expenses, such as lab supplies, poster production costs, books, registration and travel to attend and present research at a professional meeting.  

  • Housing allowance: up to $1,000 per participant.  

Research Education Funding Instruments:
  • NCI awards Research Education Cooperative Agreements (UE5)
  • NCI awards Research Education Grant Projects (R25)
Research Education Contacts:

NCI R25 Program Director(s) 
Email: [email protected] 

NCI Youth Enjoy Science Program Director(s) 
Email: [email protected]  

Small Business
In addition to our Small Business overview, consider the following NCI-specific information.
Small Business Interest Areas:

NCI supports the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs by engaging domestic small business concerns in federal cancer research and development that has the potential for commercialization. 

Phase IIB & Commercialization Readiness Pilot (CRP):
NCI accepts Phase IIB SBIR projects
NCI accepts Commercialization Readiness Pilot (CRP) projects
Clinical Trials:
NCI accepts clinical trials through the SBIR programs
NCI accepts clinical trials through the STTR programs
NCI accepts clinical trials through the Phase IIB SBIR program
NCI does not accept clinical trials through the Commercialization Readiness Pilot (CRP)
Small Business Contact:

NCI SBIR Development Center

[email protected]


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