NIH Extramural Nexus (News)

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2025


NIH Extramural Loan Repayment Programs: Application Cycle Opening and New Website Location

We are pleased to announce that the application period to apply for FY 2026 NIH Extramural Loan Repayment Program (LRP) awards will open on September 1, 2025 and close on November 20, 2025.

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Updates to NIH Inclusion Policy

When you prepare inclusion plans for your next applications or data for progress reports, review the updated NIH Policy and Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research, effective August 16, 2025 for both new and ongoing clinical research projects.

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We’ve Moved: The NIH Scientific Data Sharing Pages are Now on the NIH Grants & Funding Site

Information on NIH’s scientific data sharing policies and data repositories can now be found on the NIH Grants & Funding site – nearer the other information you need to start an application or manage an award. 

New Resources

Share Your Feedback on Maximizing Research Funds by Limiting Allowable Publication Costs

NIH has released a request for information (RFI) regarding policy options to maximize research funds by limiting allowable publication costs (APCs).   

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Apply Responsibly: Policy on AI Use in NIH Research Applications and Limiting Submissions per PI

NIH has recently announced a new policy that will continue to support originality, creativity, and fairness in the research application process. 

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Flexibilities for Registration and Results Reporting of Prospective Basic Experimental Studies with Human Participants

NIH is indefinitely extending the period of delayed enforcement for registration and results reporting for basic experimental studies involving humans (BESH) responsive to designated BESH NOFOs, including those with application due dates on or after September 25, 2025.

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Short-Term Supplement Model for Human Subjects Research Supported by Foreign Subawards

To address concerns for participant safety risks for ongoing projects, NIH has established a short-term supplement model to support clinical research and clinical trials conducted under an active foreign subaward.

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How Does the NIH Initiative to Prioritize Human-Based Research Affect Research Proposing the Use of Laboratory Animals?

In July 2025, NIH announced it will no longer develop new funding opportunities focused exclusively on animal models of human disease. Rather, going forward, new funding opportunities will be designed more broadly with language that also encourages various approaches be considered.

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NIH Fellowship Funding Opportunities Are Here

Updated funding opportunities for NIH fellowships are below and also available on the NIH Guide for Grants and Contracts and Grants.gov. NIH fellowships are open to early career scientists, including at the predoctoral and postdoctoral level, and are designed to provide mentored research training to enable skills’ development and experiences needed to transition into careers in the biomedical research workforce. 

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NIH Funding Announcements to Align with NIH Initiative to Prioritize Human-based Research

On April 29, NIH announced it is prioritizing human-focused research and reducing animal use in research. To further this initiative, all new Notices of Funding Opportunity that relate to animal model systems (NOFOs) must now also support human-focused approaches such as clinical trials, real world data, or new approach methods (NAMs).

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