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2025
Why Did NIH Expire Some Funding Opportunities Because of the Simplified Review Framework, and What Does It Mean for My Application?
The simplified review framework went into effect earlier in 2025, and NIH has been busy preparing staff, peer reviewers, and study section chairs for its arrival at summer 2025 review meetings. To avoid confusion and reduce reviewer burden at review meetings, NIH has expired identified NOFOs that were not expired or reissued as indicated in the implementation plan shared in early 2024.
Protecting Human Genomic Data When Developing Generative Artificial Intelligence Tools and Applications
NIH issued a Guide notice (NOT-OD-25-081) clarifying how to protect human genomic data obtained from NIH controlled-access repositories when using and developing generative artificial intelligence models consistent with the Genomic Data Sharing Policy.
Automatic Extension of Early Stage Investigator Status to Address Recent Delays
NIH has granted the automatic extension of Early Stage Investigator (ESI) eligibility. This extension addresses delays impacting grant application submissions, peer review, or award processing timelines between January 1, 2025, and May 31, 2025.
Reminder About Inclusion of Participants in Clinical Research
NIH continues to follow all laws (e.g., 42 USC 289a-2) and existing NIH policies that help NIH ensure clinical research includes the appropriate participant demographics to make certain the scientific question under study is addressed in a robust and generalizable manner.
New NIH Foreign Subaward Structure Enhances Integrity, Accountability, Oversight, and National Security of NIH Funded Research
Effective with the next NIH award cycle, all NIH-funded research involving foreign subawards must be structured as subprojects directly linked to the prime award. Foreign subawards are prohibited from being nested under the parent grant.
Accelerating Implementation of the NIH 2024 Public Access Policy
NIH has announced that the 2024 NIH Public Access Policy will now go into effect on July 1, 2025.
Reminder: Application Requirements for Projects Involving Activities Outside of the United States or Partnerships with International Collaborators
NIH would like to remind the extramural research community about long-standing application requirements for projects involving activities outside of the United States or partnerships with international collaborators.
New Home for Extramural Nexus on the NIH Grants and Funding Website
Your source for NIH grants news has moved to the NIH Grants and Funding website, creating a one-stop shop for your journey through the grants process! The Extramural Nexus news content is now next to the policy and process resources you need.