How Can You Effectively Prepare NIH Research Project Grant Applications for Due Dates in 2025 and Beyond?

NIH has been hard at work over the last two years developing guidance and training to help prepare the community for the implementation of the simplified review framework. That framework went into effect on January 25, 2025 and applies to applications for most research project grants.

We are often asked how the new framework will affect the preparation of applications. The simplified review framework is a new way of reviewing the same research strategies you’ve always developed, which means neither the components nor the structure of your application are expected to change.

As always, applicants should be responsive to the Notice of Funding Opportunity (NOFO) that they are applying to, especially Sections IV. Application and Submission Information and V.  Application Review Information.

Other Information

• Applicant Guidance for Simplifying the Review Framework
• How to Apply – Application Guide
• Recent Changes Implemented for Due Dates on or after January 25, 2025
• NIH All About Grants Podcast: Simplified Review Framework