PA-25-306 - NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) is used for the submission of applications to the following Notices of Special Interest (NOSIs)
On This Page: 62
Active NOSIs
| Title | Notice Number | Organization | Release Date |
Expiration Date |
Activity Code(s) |
|---|
Expired NOSIs
| Title | Notice Number | Organization | Release Date |
Expiration Date |
Activity Code(s) |
|---|---|---|---|---|---|
| Notice of Special Interest (NOSI): Discovery and Development of Natural Products to Treat Substance Use Disorders (SUDs) | NOT-DA-25-032 | NIDA NCCIH | Nov 25, 2024 | Sep 9, 2025 | R01, UG3/UH3, U01, R21 |
| Notice of Special Interest (NOSI): Effectiveness of Mobile Health Clinics to Advance Health Equity | NOT-MD-24-022 | NIMHD NICHD ODP THRO | Sep 26, 2024 | Sep 9, 2025 | R01, K01, R21, K08, K99/R00, K23 |
| Notice of Special Interest (NOSI): Consequences of Prenatal Fentanyl Exposure | NOT-DA-26-003 | NIDA | Sep 13, 2024 | Sep 9, 2025 | R21, R01, R03 |
| Notice of Special Interest (NOSI): Application of Artificial Intelligence in Treatment Development for Substance Use Disorders | NOT-DA-26-005 | NIDA | Sep 13, 2024 | Sep 9, 2025 | R03, R01, R21 |
| Notice of Special Interest (NOSI): Model-informed Drug Development (MIDD) Approaches to Facilitate the Development of Therapeutics for Substance Use Disorders | NOT-DA-26-002 | NIDA | Aug 27, 2024 | Sep 9, 2025 | R01, R21, R03 |
| Notice of Special Interest (NOSI): Fundamental Science Research on Complementary and Integrative Health Approaches, Including Natural Products or Mind and Body Interventions | NOT-AT-24-041 | NCCIH | Aug 13, 2024 | Sep 9, 2025 | R21, R01 |
| Notice of Special Interest (NOSI): Supporting Research Using the Resources from the Osteoarthritis Initiative (OAI) | NOT-AR-24-019 | NIAMS NIA | Aug 8, 2024 | Sep 9, 2025 | R01, R21 |
| Notice of Special Interest (NOSI): Ending the HIV Epidemic (EHE) | NOT-AI-24-059 | NIAID NHLBI NIA NIAAA NICHD NIDA NIMH NIMHD NINR OAR | Aug 6, 2024 | Sep 9, 2025 | R01, R34, R21 |
| Notice of Special Interest (NOSI): Impact of Financing and Payment Mechanisms to Improve Behavioral Health Access, Utilization and Outcomes | NOT-MH-24-270 | NIMH NIDA | Jul 25, 2024 | Sep 9, 2025 | K01, K08, K99/R00, K23, R01, R03, R21, R34 |
| Notice of Special Interest (NOSI): Advancing Research on SUD with brain-based computational models | NOT-DA-26-001 | NIDA | Jul 2, 2024 | Sep 9, 2025 | R01, R21, R61/R33, K01, R15, R03, K99/R00 |
| Notice of Special Interest (NOSI): Improving Adherence to Treatment and Prevention Regimens and Maintenance of Health Behaviors to Promote Health | NOT-OD-24-146 | OBSSR NCCIH NCI NEI NHLBI NIA NIDA NIMH NIMHD NINR OAR ODP ORWH | Jun 24, 2024 | Sep 9, 2025 | P01, P30, R01, R03, UG3/UH3, R34, U24, R41/R42, R21, R43/R44, R21/R33, R61 |
| Notice of Special Interest (NOSI): Exploring the Effects of Endocannabinoids and Exogenous Cannabinoids on Brain Development | NOT-DA-25-030 | NIDA | Apr 30, 2024 | Sep 9, 2025 | R01, K01, K25, R21, R03, K08, K99/R00 |
| Notice of Special Interest: Womens Health Research | NOT-OD-24-079 | ORWH FIC NCATS NCCIH NCI NEI NHGRI NHLBI NIA NIAAA NIAID NIAMS NIBIB NICHD NIDA NIDCD NIDCR NIDDK NIEHS NIGMS NIMH NIMHD NINDS NINR NLM OAR OBSSR ODP ODS ODSS | Mar 26, 2024 | Sep 9, 2025 | R15, R01, K01, R16, K08, R21, K43, F31, R43/R44, R41/R42, F30, R03, K23, F32, R34 |
| Notice of Special Interest (NOSI): Developing and Testing Multi-level Physical Activity Interventions to Improve Health and Well-Being | NOT-OD-24-058 | ODP NCCIH NCI NIA NIAMS NICHD NIMHD NINR OBSSR ODS ORWH | Feb 20, 2024 | Sep 9, 2025 | U24, R01, R21, R34, UG3/UH3, R03 |
| Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence/Machine Learning Tools for Improved Assessment in Biomedical and Behavioral Research | NOT-CA-24-031 | NCI NHLBI NIA NIDA NIMH NINR OBSSR ODSS | Feb 15, 2024 | Jul 6, 2025 | R61/R33, R01, R21, R43/R44, R34, R41/R42 |
| Notice of Special Interest (NOSI): Quantum Sensing Technologies in Biomedical Applications | NOT-EB-23-022 | NIBIB NCATS NCI NEI NHLBI NIGMS | Dec 13, 2023 | Sep 9, 2025 | R35, RM1, R21, R01, U01, R15, R13, K99/R00 |
| Notice of Special Interest (NOSI): Data Informed, Place-Based Community-Engaged Research to Advance Health for All | NOT-HL-23-110 | NHLBI NCI NIDCR NIEHS NIMH NIMHD NINR OBSSR ODP ORWH | Nov 28, 2023 | Sep 9, 2025 | R01, R34, R21, UG3/UH3, K01, R03, P01, P50, K08, K23 |
| Notice of Special Interest (NOSI): Interventions to promote mental well-being in populations that experience health disparities through social, cultural, and environmental connectedness | NOT-OD-23-194 | ODP NCCIH NIA NIBIB NIDCR NIMH NIMHD OAR ORWH | Nov 6, 2023 | Sep 9, 2025 | R21, R01, R34, UG3/UH3 |
| Notice of Special Interest (NOSI): The Road to Prevention of Stillbirth | NOT-HD-23-021 | NICHD | Oct 3, 2023 | Sep 9, 2025 | F31, R03, R15, K08, R01, R21, F30, U24, R43/R44, K23, R41/R42, R25, S06, F32, U01 |
| Notice of Special Interest (NOSI): Xylazine: Understanding Its Use and the Consequences | NOT-DA-24-012 | NIDA | Aug 28, 2023 | Jan 8, 2025 | R21, R03 |
| Notice of Special Interest in Research on Family Support and Rejection in the Health and Well-Being of SGM Populations | NOT-OD-23-166 | OD NCI NIA NIAMS NICHD NIDDK NIMH NIMHD OBSSR ODP ORWH THRO | Aug 28, 2023 | Sep 9, 2025 | R21, R15, R01, R34, K25, K99/R00, K01, R03, P01, K08, K23 |
| Notice of Special Interest (NOSI): Epidemiology and Prevention in Alcohol Research | NOT-AA-23-018 | NIAAA NCI | Aug 24, 2023 | Sep 9, 2025 | R03, R21, R01, UG3/UH3, R61/R33 |
| Notice of Special Interest (NOSI): Role of social function on SUD treatment and outcomes | NOT-DA-25-026 | NIDA | Aug 1, 2023 | Sep 9, 2025 | R01, R21 |
| Notice of Special Interest (NOSI): Accelerating Research in Understudied Skin Types | NOT-AR-24-009 | NIAMS | Jul 31, 2023 | Sep 9, 2025 | R21, R01, R34 |
| Notice of Special Interest (NOSI): Advancing Biomedical Research in Pulmonary Non-Tuberculous Mycobacterial (NTM) Infections | NOT-AI-23-050 | NIAID | Jun 27, 2023 | Sep 9, 2025 | R21, R41/R42, R43/R44, R01, U44 |
| Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses | NOT-AI-23-048 | NIAID | Jun 15, 2023 | Sep 9, 2025 | R01, R43/R44, U44, R41/R42, R21 |
| Notice of Special Interest (NOSI): Impacts of Psychedelic and Dissociative Drug Policy Changes on Public Health Outcomes | NOT-DA-24-010 | NIDA | Jun 13, 2023 | Sep 9, 2025 | R03, 333, R01, R15, R21 |
| Notice of Special Interest (NOSI): Supporting Exploratory/Developmental Research Focused on NIAMS Core Mission Areas | NOT-AR-23-006 | NIAMS | Apr 17, 2023 | Sep 9, 2025 | R21 |
| Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications. | NOT-EB-23-002 | NIBIB NCCIH NCI NHLBI NIA NIAID NICHD NIGMS | Apr 14, 2023 | Sep 9, 2025 | R01, R21, R35, R41/R42, R43/R44 |
| Notice of Special Interest (NOSI): Encouraging Womens Health Research within the NIDCD Mission Areas | NOT-DC-23-006 | NIDCD | Mar 28, 2023 | Sep 9, 2025 | R15, R21, R01 |
| Notice of Special Interest: Advancing mHealth Interventions for Understanding and Preventing Alcohol-Related Domestic Violence | NOT-AA-23-003 | NIAAA | Mar 6, 2023 | Sep 9, 2025 | R01, R21, R34, K99/R00 |
| Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine | NOT-AI-23-031 | NIAID | Feb 23, 2023 | Sep 9, 2025 | R01, R41/R42, R43/R44, R21, U44 |
| Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services | NOT-MH-23-140 | NIMH NIDA ORWH | Jan 18, 2023 | May 8, 2025 | R21, R01, R34 |
| Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases | NOT-DA-22-048 | NIDA NCI NIDCR | Jan 9, 2023 | Sep 9, 2025 | R01, R21, DP2, DP1, K99/R00, K01, R36, K08, R15, K24 |
| Notice of Special Interest (NOSI): Firearm Injury and Mortality Prevention Research | NOT-OD-23-039 | OBSSR NCCIH NIA NIAAA NICHD NIDA NIMH NIMHD NINR ODP ORWH | Dec 16, 2022 | Sep 9, 2025 | R01, R34, R21, U24, R61/R33, UG3/UH3 |
| Notice of Special Interest (NOSI): The Neural Mechanisms of Multi-Dimensional Emotional and Social Representation | NOT-MH-23-120 | NIMH | Dec 7, 2022 | Jan 8, 2025 | R21, R01, R03, R15 |
| Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine | NOT-AI-23-007 | NIAID | Nov 25, 2022 | Sep 9, 2025 | R21, R41/R42, R43/R44, R01 |
| Notice of Special Interest (NOSI): Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R01, R21, R03) | NOT-DA-23-012 | NIDA | Nov 2, 2022 | Sep 9, 2025 | R01, R03, R21 |
| Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NIDA Populations of Interest | NOT-DA-22-084 | NIDA | Oct 20, 2022 | Sep 9, 2025 | R15, R21, R01, R03 |
| Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NICHD Populations of Interest | NOT-HD-22-038 | NICHD NIDA | Sep 14, 2022 | Jan 8, 2025 | R15, R03, R01, R21 |
| Notice of Special Interest (NOSI): Research on the Health of Bisexual and Bisexual+ People | NOT-OD-22-166 | OD NCCIH NIA NIAAA NIAID NICHD NIDA NIDCR NIMH NIMHD NINDS ODP | Aug 11, 2022 | May 8, 2025 | K24, U01, R01, K01, R15, R03, K76, R34, K99/R00, T32, F32, UG3/UH3, R21, K23, F31 |
| Notice of Special Interest (NOSI): Community-Based Participatory Research (CBPR) Initiative in Reducing and Eliminating Health Disparities with a focus on addressing diverse representation in research on Down syndrome (R21 Clinical Trial Optional) | NOT-OD-22-142 | OD NCI NEI NHLBI NIA NIAMS NICHD NIDCD NIDCR NIMHD NINDS | Aug 5, 2022 | Mar 17, 2025 | R21 |
| Notice of Special Interest (NOSI): Promoting Mechanistic Research on Therapeutic and Other Biological Properties of Minor Cannabinoids and Terpenes | NOT-AT-22-027 | NCCIH NCI NEI NIA NIAAA NIDA NIDCR NINDS ODS ORWH | Jul 27, 2022 | Jul 1, 2025 | R21, R01, UG3/UH3 |
| Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening | NOT-OD-22-179 | ODP NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | Jul 14, 2022 | May 8, 2025 | R21, R01, R61/R33, UG3/UH3, R34, U01 |
| Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan | NOT-OD-22-178 | ODP NCI NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | Jul 14, 2022 | Apr 16, 2025 | R21, R01, UG3/UH3, R61/R33, R34, R03 |
| Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes | NOT-OD-22-167 | OBSSR NIA NIAAA NICHD NIDA NIDCD NIDCR NIMH NIMHD NINR ODP ORWH | Jul 8, 2022 | Sep 9, 2025 | R21, R01, R34, UG3/UH3 |
| Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities | NOT-OD-22-154 | ODP NCI NHLBI NIAAA NIAMS NIDCR NIEHS NIMHD NINDS OBSSR ORWH | Jun 14, 2022 | Sep 9, 2025 | R01, R21, R34, R03, UG3/UH3 |
| Notice of Special Interest (NOSI): Climate Change and Health | NOT-ES-22-006 | NIEHS FIC NCI NHGRI NHLBI NIA NIAID NIAMS NICHD NIDCR NIMH NIMHD NINDS NINR NLM ODP | Jun 1, 2022 | May 8, 2025 | R21, F31, D43, K01, R03, K43, K99/R00, U01, U19, R01, F32, K23, F30, R21/R33 |
| Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan | NOT-OD-22-106 | ODP NCI NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | May 12, 2022 | May 8, 2025 | R03, R01, R34, R21, UG3/UH3, R61/R33, 333 |
| Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening | NOT-OD-22-107 | ODP NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | May 12, 2022 | May 8, 2025 | 333, R01, R34, R21, R61/R33, U01, UG3/UH3 |
| Notice of Special Interest (NOSI): Research using implementation science to support the delivery of evidence-based practices in community-based mental or general medical healthcare settings | NOT-MH-22-170 | NIMH NIDA | Mar 25, 2022 | May 8, 2025 | R21, R01, R34 |
| Notice of Special Interest (NOSI): Leveraging Data Science to Bring Actionable Insights for Substance Use Prevention and Treatment | NOT-DA-23-006 | NIDA | Mar 1, 2022 | Sep 8, 2025 | R21, R01, R03, 333 |
| Notice of Special Interest (NOSI): Public Health Research on Cannabis | NOT-DA-22-003 | NIDA | Feb 18, 2022 | May 5, 2025 | R21, R01, 333, R03 |
| Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services | NOT-MH-22-110 | NIMH NIDA ORWH | Feb 8, 2022 | May 8, 2025 | R21, R01, R34, R43/R44 |
| Notice of Special Interest: NIMH Priorities on Research on Aggression and Violence Against Others | NOT-MH-22-095 | NIMH | Feb 3, 2022 | Jan 8, 2025 | R36, R01, R34, R21, F32, R21/R33, R03, R61/R33, U01, K08, R15, K23, P50, F30, K99/R00, F31, K22, K01 |
| Notice of Special Interest (NOSI): Research to Prevent Drug Use, Misuse and Addiction | NOT-DA-23-001 | NIDA ODP | Jan 21, 2022 | May 8, 2025 | R01, R21, R34, R03 |
| Notice of Special Interest (NOSI): COVID-19 Pandemic Mental Health Research | NOT-MH-22-100 | NIMH | Jan 19, 2022 | Jan 8, 2025 | R21, R34, R01 |
| Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients Use of Genomic Information | NOT-HG-22-011 | NHGRI | Jan 6, 2022 | Sep 8, 2025 | R01, R21, U24, R43/R44, R41/R42 |
| Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging | NOT-AG-22-004 | NIA | Dec 22, 2021 | Jan 8, 2025 | F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19 |
| Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College | NOT-AA-22-001 | NIAAA | Dec 9, 2021 | Sep 9, 2025 | R21, R03, R01, R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Accelerating Progress in Celiac Disease Research | NOT-AI-22-004 | NIAID NIAMS NCCIH NCI | Nov 23, 2021 | Jan 8, 2025 | R03, R21, U01, U44, R01, R34, P01, R61/R33 |
| Notice of Special Interest (NOSI): Advancing HIV/AIDS Research through Computational Neuroscience | NOT-DA-21-030 | NIDA | Jun 22, 2021 | Jan 8, 2025 | R01, R21, R03, DP2, DP1, K99/R00, K01, R36, P01, R15, K24 |

