PA-24-247 - PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

On This Page: 49

Active NOSIs

Title Notice Number Organization Release
Date		 Expiration
Date		 Activity
Code(s)

Expired NOSIs

Title Notice Number Organization Release
Date		 Expiration
Date		 Activity
Code(s)
Notice of Special Interest (NOSI): Quantum Sensing in Biomedical Applications (SBIR/STTR) NOT-EY-24-014 NEI NCATS NCI NHLBI NIBIB Sep 20, 2024 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest: Small Business Solutions to Enable Regional Genomic Medicine eConsult Services NOT-HG-24-041 NHGRI Sep 4, 2024 Sep 9, 2025 R41/R42, R43/R44
Notice of Special Interest: Small Business Solutions to Assist Genomics-Enabled Learning Health Systems (gLHS) NOT-HG-24-040 NHGRI Sep 4, 2024 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Precision Imaging for Enhanced Diagnosis and Treatment of Oral Lesions NOT-DE-25-034 NIDCR Aug 30, 2024 Sep 9, 2025 UG3/UH3, R43/R44, R01, R41/R42, R21
Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application NOT-HG-24-036 NHGRI Jul 25, 2024 Sep 9, 2025 R01, R41/R42, R21, R43/R44
Notice of Special Interest (NOSI): Epigenetic Modulation of HBV cccDNA and integrated HBV DNA (iDNA): Implications for Epigenetic Treatment Strategies Against HBV in HIV/HBV Co-Infection NOT-AI-24-050 NIAID Jun 28, 2024 Sep 9, 2025 R41/R42, R43/R44, R01, R21
Notice of Special Interest (NOSI): Improving Adherence to Treatment and Prevention Regimens and Maintenance of Health Behaviors to Promote Health NOT-OD-24-146 OBSSR NCCIH NCI NEI NHLBI NIA NIDA NIMH NIMHD NINR OAR ODP ORWH Jun 24, 2024 Sep 9, 2025 P01, P30, R01, R03, UG3/UH3, R34, U24, R41/R42, R21, R43/R44, R21/R33, R61
Notice of Special Interest (NOSI): Translating Biomaterials-Based Technologies to Commercially Viable Products NOT-EB-24-001 NIBIB NCATS NCCIH NHLBI NIDCR Mar 29, 2024 Sep 9, 2025 R41/R42, R43/R44
Notice of Special Interest (NOSI): Research to Stimulate Development of Diagnostics, Therapeutics, and Vaccines for Herpes Simplex Virus (HSV) NOT-AI-24-028 NIAID Mar 27, 2024 Sep 9, 2025 R21, R41/R42, R43/R44, R03, R01
Notice of Special Interest: Womens Health Research NOT-OD-24-079 ORWH FIC NCATS NCCIH NCI NEI NHGRI NHLBI NIA NIAAA NIAID NIAMS NIBIB NICHD NIDA NIDCD NIDCR NIDDK NIEHS NIGMS NIMH NIMHD NINDS NINR NLM OAR OBSSR ODP ODS ODSS Mar 26, 2024 Sep 9, 2025 R15, R01, K01, R16, K08, R21, K43, F31, R43/R44, R41/R42, F30, R03, K23, F32, R34
Notice of Special Interest (NOSI): Development of Imaging Techniques for High Resolution and Functional Scanning of In Vivo Human Sensory and Communication Systems NOT-DC-24-025 NIDCD Mar 22, 2024 Sep 9, 2025 R01, U01, R43/R44, R41/R42, R21
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence/Machine Learning Tools for Improved Assessment in Biomedical and Behavioral Research NOT-CA-24-031 NCI NHLBI NIA NIDA NIMH NINR OBSSR ODSS Feb 15, 2024 Jul 6, 2025 R61/R33, R01, R21, R43/R44, R34, R41/R42
Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health NOT-ES-24-002 NIEHS NCATS NCCIH NEI NHLBI NIA NIAID NIAMS NLM Feb 15, 2024 Apr 6, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Genomic Medicine Research through Small Businesses NOT-HG-24-016 NHGRI Feb 14, 2024 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): RNA Delivery Technologies to Allow Specific Tissue Target Homing (RNA-DASH) NOT-AI-24-007 NIAID NCATS NCI Feb 2, 2024 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Translation of BRAIN Initiative Technologies to the Marketplace NOT-MH-24-115 NIMH NCCIH NEI NIA NIAAA NIBIB NICHD NIDA NIDCD NINDS Jan 8, 2024 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application NOT-HG-24-012 NHGRI Dec 20, 2023 Sep 30, 2024 R01, R21, R43/R44, R41/R42
Notice of Special Interest (NOSI): SBIR/STTR High-Priority Areas for Digital Mental Health Innovations NOT-MH-24-120 NIMH Nov 29, 2023 Sep 9, 2025 R41/R42, R43/R44
Notice of Special Interest (NOSI): SBIR/STTR Program Priorities to Bridge Gaps in Advancing the NIMH Mission NOT-MH-24-110 NIMH Nov 29, 2023 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives NOT-AI-23-076 NIAID Oct 31, 2023 Sep 9, 2025 R03, R01, R21, R41/R42, R43/R44
Notice of Special Interest (NOSI): Advancing Genomic Medicine Research through Small Businesses NOT-HG-24-002 NHGRI Oct 11, 2023 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): The Road to Prevention of Stillbirth NOT-HD-23-021 NICHD Oct 3, 2023 Sep 9, 2025 F31, R03, R15, K08, R01, R21, F30, U24, R43/R44, K23, R41/R42, R25, S06, F32, U01
Notice of Special Interest (NOSI): Quantum Sensing in Biomedical Applications (SBIR/STRR) NOT-EY-23-009 NEI NCATS NCI Sep 6, 2023 Sep 6, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): Small Business Initiatives for Innovative tools and Technologies for Improving Outcomes for Maternal Health NOT-EB-23-005 NIBIB NCATS NHLBI NIAMS NIMH NIMHD NINDS ORWH Jul 26, 2023 Sep 9, 2025 U44, R43/R44, R41/R42
Notice of Special Interest (NOSI): Innovative Technologies to develop novel tools to prevent and treat HIV in underserved populations NOT-MH-23-200 NIMH Jul 18, 2023 Sep 9, 2025 R41/R42, R43/R44
Notice of Special Interest (NOSI): Advancing Biomedical Research in Pulmonary Non-Tuberculous Mycobacterial (NTM) Infections NOT-AI-23-050 NIAID Jun 27, 2023 Sep 9, 2025 R21, R41/R42, R43/R44, R01, U44
Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives NOT-AI-23-049 NIAID Jun 23, 2023 Sep 9, 2025 R03, R01, R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses NOT-AI-23-048 NIAID Jun 15, 2023 Sep 9, 2025 R01, R43/R44, U44, R41/R42, R21
Notice of Special Interest (NOSI): Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults NOT-MH-23-250 NIMH May 19, 2023 Sep 9, 2025 K43, R41/R42, R21, K08, R25, K99/R00, T32, K01, F30, R34, R03, F31, R15, R43/R44, K24, K23, F32, R01
Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications. NOT-EB-23-002 NIBIB NCCIH NCI NHLBI NIA NIAID NICHD NIGMS Apr 14, 2023 Sep 9, 2025 R01, R21, R35, R41/R42, R43/R44
Notice of Special Interest (NOSI): Development of Innovative Informatics and Data Science Technologies, Tools, and Methods for Vision Research NOT-EY-23-005 NEI Apr 3, 2023 Sep 9, 2025 R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): Promoting Language and Communication in Minimally Verbal/Non-Speaking Individuals with Autism NOT-DC-23-009 NIDCD Apr 3, 2023 Sep 9, 2025 R13, R15, R01, U01, R21, R43/R44, R41/R42, R03
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-031 NIAID Feb 23, 2023 Sep 9, 2025 R01, R41/R42, R43/R44, R21, U44
Notice of Special Interest (NOSI): Small Business Digital Technologies for Early Detection, Characterization and Monitoring of Senescence-Related Changes NOT-AG-23-004 NIA Feb 7, 2023 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Development of Functional Assay Sites to Evaluate Candidate -Omics Variants Associated with Heart, Lung, Blood, or Sleep Disease (R01, R41, R42, R43, R44) NOT-HL-23-066 NHLBI Jan 31, 2023 Sep 9, 2025 R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Optimization of Data Storage and Utilization for the Sequence Read Archive (SRA) NOT-GM-23-015 NIGMS NLM ODSS Dec 14, 2022 Sep 9, 2025 R41/R42, R43/R44, R01, K08, RM1, R21, K25, K99/R00, K23, F30, F32, F33, F31, R16, R35, R15
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-007 NIAID Nov 25, 2022 Sep 9, 2025 R21, R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Advancing Research for Tickborne Diseases (TBDs) NOT-AI-23-013 NIAID NIAMS NIMH NINDS Nov 25, 2022 Sep 9, 2025 R43/R44, R15, R01, R21, R03, R41/R42
Notice of Special Interest (NOSI): Advancing Development of Rapid Point-of-Care Hepatitis C Virus Diagnostics NOT-AI-23-001 NIAID NCI NIBIB Nov 23, 2022 Sep 9, 2025 R01, R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Validation for Early Detection of Cancers NOT-CA-23-004 NCI Oct 17, 2022 Jul 2, 2025 R43/R44, R21, R01, UH2/UH3, R41/R42, U01
Notice of Special Interest (NOSI): Towards Developing a Cure for HBV in HIV/HBV Co-Infection NOT-AI-22-043 NIAID Apr 29, 2022 May 8, 2025 R01, R41/R42, R21, R43/R44
Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities NOT-EY-22-004 NEI NIMHD Feb 14, 2022 Jan 25, 2025 R01, UG1, F31, R21, 333, K99/R00, K08, F30, K23, R43/R44, R34, R41/R42, F32
Notice of Special Interest (NOSI): Advancing NEI AGI Research on newly Identified Factors Into Models of Visual System Regeneration NOT-EY-22-002 NEI Jan 10, 2022 Feb 10, 2025 R43/R44, R21, R15, R41/R42, R01, R24
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging NOT-AG-22-004 NIA Dec 22, 2021 Jan 8, 2025 F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19
Notice of Special Interest (NOSI): Methods Development for Genomic Studies of Genetic Variation, Function, and Disease NOT-HG-22-007 NHGRI Dec 9, 2021 Nov 5, 2024 R41/R42, R01, R43/R44, R21
Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College NOT-AA-22-001 NIAAA Dec 9, 2021 Sep 9, 2025 R21, R03, R01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 NIDCR Sep 1, 2021 Sep 5, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Genomics Education Interactive Digital Media Resources (SBIR/STTR) NOT-HG-21-038 NHGRI Aug 26, 2021 Dec 31, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): National Cancer Institute SBIR/STTR Program Announcement Regarding Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings NOT-CA-21-062 NCI Jul 23, 2021 Sep 7, 2024 R43/R44, R41/R42
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