Release
Date: March 29, 2012
Estimated
Publication Date of Announcement: Late Spring 2012
First
Estimated Application Due Date: July 26, 2012
Earliest
Estimated Award Date: Spring 2013
Earliest
Estimated Start Date: March 1, 2013
National Human Genome Research Institute (NHGRI)
The NHGRI intends to publish a Funding Opportunity
Announcement (FOA) to solicit grant applications for research on exploring, within
an active clinical setting, the application of genomic sequence data to the
care of patients. This will be a reissue, with modifications, of RFA-HG-10-017
that solicited applications for Clinical Sequencing Exploratory Research (CSER)
Program Study Investigators. Applications submitted in response to this FOA
will address critical questions about the application of genomic sequencing to
clinical care of individual patients, from generation of genomic sequence data,
to interpretation and translation of the data for the physician, to
communication to the patient, including an examination of the ethical, legal,
economic and psychosocial implications of bringing broad genomic data into the
clinic. Further details of the CSER Program are available in RFA-HG-10-017 (https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-10-017.html).
This Notice is being provided to allow potential applicants sufficient time to
develop meaningful collaborations and responsive projects.
The FOA is expected to be published in late Spring, 2012 with an expected
receipt date in Summer, 2012.
This FOA will utilize the U01 activity code. Details of the planned Funding
Opportunity Announcement (FOA) are provided below.
This Notice encourages investigators with expertise and insights into the clinical application of genome-scale sequence data, including the relevant ethical, legal and psychosocial issues, to begin to consider applying for this new FOA. The goals of the CSER program are to develop and apply methods to integrate sequencing into the clinic, as well as to study relevant ethical, legal, economic and psychosocial issues involved in responsibly applying personal genomic sequence data to medical care. Applications submitted in response to the CSER Project FOA will include three separate, but highly integrated sub-projects: 1) Clinical Genomics Study; 2) Sequencing, Analysis and Interpretation of Sequencing Data, and 3) Ethical, Legal, Economic and Psychosocial Implications Research, plus a Management Core describing the study management plan.
APPLICATIONS ARE NOT BEING SOLICITED AT THIS TIME.
Please direct all inquiries to:
Bradley A. Ozenberger, Ph.D.
Program Director
National Human Genome Research Institute
5635 Fishers Lane
Suite 4076, MSC 9305
Bethesda, MD 20892
Telephone: 301-496-7531
Email: bozenberger@mail.nih.gov
Jean E. McEwen, J.D., Ph.D.
Division of Extramural Research
National Human Genome Research Institute
5635 Fishers Lane
Suite 4076, MSC 9305
Bethesda, MD 20892-9305
Telephone: 301-402-4997
Email: mcewenj@mail.nih.gov