NOTICE OF LIMITED COMPETITION FOR COMPETING APPLICATIONS: NIDDK AFRICAN 
AMERICAN STUDY OF KIDNEY DISEASE (AASK) COHORT STUDY

RELEASE DATE:  November 8, 2002

NOTICE: NOT-DK-02-012

National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK)
 (http://www.niddk.nih.gov)

The NIDDK is requesting competing applications from the participating centers 
in the African American Study of Kidney Disease (AASK), which was competed in 
1994. This initiative is to support a prospective, observational study that 
will be an extension of the AASK clinical trial.  AASK is a randomized 
multicenter clinical trial to investigate whether a specific class of anti-
hypertensive drugs (beta-adrenergic blockers, calcium channel blockers, or 
angiotension converting enzyme inhibitors) and/or the level of blood pressure 
control (MAP of 102-107 mmHg or 92 mmHg) will influence the progression of 
hypertensive kidney disease in African Americans.   The existing AASK 
Clinical Centers and Data Coordinating Center possesses the leadership, 
organization, infrastructure, staffing and study population base to address 
the important objectives of the Cohort Study. The AASK Cohort Study will 
investigate the environmental, socioeconomic, genetic, physiologic, and other 
co-morbid factors that influence the progression of kidney disease in a well-
characterized cohort of African Americans with hypertensive kidney disease.

NIDDK staff will contact the current grantees directly regarding application 
procedures and format.

INQUIRES

Written and telephone inquiries concerning this may be directed to :

Lawrence Agodoa, M.D.
Director, Office of Minority Health Research Coordination
National Institute of Diabetes and Digestive and Kidney Diseases
6707 Democracy Boulevard, Room 653
Bethesda, MD 20892-5454
Telephone: (301) 594-1932
Fax: (301) 594-9358
Email: [email protected]

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